Spravato Treatment
in Palisade, CO
Myndful Wellness offers hope and advanced treatment with spravato in Palisade, CO, for adults with persistent depression. From our comfortable clinic in Grand Junction, we provide residents of the Western Slope with access to this innovative FDA-approved nasal spray. Our compassionate approach integrates spravato into a comprehensive mental wellness plan, supervised by our qualified psychiatric team to ensure your safety and comfort.

What Is Spravato in Palisade, CO?
FDA-Approved Treatment
Spravato (esketamine) is an FDA-approved prescription medication for adults with treatment-resistant depression (TRD). It is intended for patients who have not responded adequately to at least two different oral antidepressants.
Unique Mechanism of Action
Unlike most oral antidepressants that primarily target serotonin, norepinephrine, or dopamine, spravato works on the glutamate pathway. As an NMDA receptor antagonist, it offers a different approach to managing depressive symptoms.
Nasal Spray Formulation
The treatment is administered as a simple-to-use nasal spray that you will use yourself in our office. This delivery method allows for controlled, professional dosing under the guidance of our trained medical staff.
Supervised In-Office Sessions
For your safety, all spravato treatments are conducted in our comfortable, private treatment alcoves. A licensed psychiatric provider remains on-site to monitor your session and provide clinical support as needed.
Integrated Care Plan
Spravato is not a standalone treatment but is part of a comprehensive care strategy. It is used in conjunction with an oral antidepressant and may be combined with psychotherapy to support your long-term mental health goals.
REMS Certified Center
We are a REMS (Risk Evaluation and Mitigation Strategy) certified center. This certification ensures we adhere to strict safety protocols for prescribing and administering spravato, prioritizing patient safety above all.
Rapid-Acting Potential
Some patients may experience a reduction in depressive symptoms more quickly than with traditional oral medications. This makes it a valuable option for those seeking prompt relief as part of their overall treatment plan.
Why Choose Our Compassionate Care?
Founded by Jessica Schmalz, PMHNP-BC, Myndful Wellness is built on a foundation of compassionate, individualized mental health care. During every spravato session, a licensed psychiatric provider is on-site to ensure your safety, offer support, and monitor your progress. We are a REMS certified center, committed to providing care in a calm, supportive space where your well-being is the priority.

Our Spravato Process

Initial Consultation
Your journey begins with a thorough psychiatric evaluation to determine if spravato is an appropriate treatment for you. We will review your mental health history, past treatments, and current symptoms to ensure this is a safe and suitable option.
Personalized Treatment Plan
If you are a candidate, we will create a personalized care plan. This includes establishing the frequency of your spravato sessions, which is typically once or twice a week initially, and coordinating it with your ongoing antidepressant medication.
Your Treatment Session
On treatment day, you will relax in a private, comfortable alcove. You will self-administer the spravato nasal spray under the supervision of our staff, who will be available to support you throughout the session.
Post-Treatment Observation
Following administration, you will remain in our office for a two-hour observation period to monitor for comfort and any potential short-term effects. You must arrange for a friend or family member to drive you home after each session.
Ongoing Care and Adjustment
Your progress will be continuously evaluated through monthly check-ins with our psychiatric provider. As you progress, the frequency of your spravato treatments may be adjusted to maintain your mental wellness and symptom relief.

Who Benefits from Spravato?
Myndful Wellness offers hope and advanced treatment with spravato in Palisade, CO, for adults with persistent depression. From our comfortable clinic in Grand Junction, we provide residents of the Western Slope with access to this innovative FDA-approved nasal spray. Our compassionate approach integrates spravato into a comprehensive mental wellness plan, supervised by our qualified psychiatric team to ensure your safety and comfort.
Conditions We Treat

- Adults with Treatment-Resistant Depression (TRD)
- Those with Major Depressive Disorder & Suicidal Thoughts
- Individuals Unresponsive to Prior Antidepressants
- Patients Seeking a Clinically Supervised Treatment
- Those Committed to a Comprehensive Treatment Plan

Patient Experiences

“I am so grateful for the care I received at Myndful wellness. After struggling with my mental health for a long time, TMS and (Spravato)ketamine treatments helped me tremendously. I have noticed significant improvements in my mood, energy, and overall quality of life.”

“This place is awesome .I do my spravato treatments here. Jessica and Brittany are both very nice and professional especially Brittany and have always made me feel comfortable and not just like another patient.”

“I have been receiving ExxoMind and Spravano treatments for the past 3 months at Myndful Wellness. I was hesitant to begin treatment treatments that may seem out of the box but was well informed of what the benefits could actually mean for my depression. As I have progressed, I have felt very informed and taken care of.”
Cost of Spravato in Palisade, CO
Myndful Wellness offers hope and advanced treatment with spravato in Palisade, CO, for adults with persistent depression. From our comfortable clinic in Grand Junction, we provide residents of the Western Slope with access to this innovative FDA-approved nasal spray. Our compassionate approach integrates spravato into a comprehensive mental wellness plan, supervised by our qualified psychiatric team to ensure your safety and comfort.
FAQ About Spravato in Palisade, CO
Is Spravato covered by insurance?
Most major insurance plans, including Medicaid, offer coverage for spravato. Our team at Myndful Wellness will assist you in verifying your benefits and exploring cost-saving programs like spravato® withMe to make treatment more accessible.
How often are Spravato treatments scheduled?
The initial treatment phase typically involves sessions once or twice a week. Over time, as your symptoms improve, the frequency may be reduced to weekly or bi-weekly maintenance sessions based on your provider’s recommendation.
Can I drive myself home after a session?
No, you cannot drive or operate heavy machinery for the rest of the day after your treatment. You must arrange for transportation home from our office after every spravato session for your safety.
Do I have to be a current patient to receive Spravato?
No, you do not need to have your other medications prescribed by our providers to be considered for spravato. We welcome referrals and can collaborate with your existing mental health providers to ensure integrated, comprehensive care.