Spravato Treatment
in Fruita, CO
Myndful Wellness offers a path to relief with spravato for adults in Fruita, CO, facing treatment-resistant depression. Our clinic provides a supportive and professional setting for this innovative FDA-approved treatment. We are dedicated to helping our neighbors find new hope and achieve long-term mental wellness through personalized care plans.

What Is Spravato in Fruita, CO?
A New Approach to Depression
Spravato (esketamine) is an FDA-approved nasal spray for adults with treatment-resistant depression (TRD). It offers a different mechanism of action than traditional oral antidepressants, providing a new option for those who haven’t found relief with other treatments.
How spravato Works
Unlike medications that primarily target serotonin or norepinephrine, spravato works on the NMDA receptor, targeting the glutamate pathway. This action is believed to help restore synaptic connections in the brain cells of people with major depressive disorder, offering a novel approach to managing complex depression.
Part of a Comprehensive Plan
Spravato is always administered in conjunction with an oral antidepressant and is part of a complete mental health strategy. Our team at Myndful Wellness integrates it with services like medication management and therapy to support your overall well-being and ensure holistic care.
FDA-Approved for TRD
This treatment is specifically indicated for adults with treatment-resistant depression (TRD), defined as depression that has not responded adequately to at least two different oral antidepressant trials. Spravato represents a significant advancement in care for this challenging condition.
For MDD with Suicidal Ideation
Spravato is also approved for adults with major depressive disorder (MDD) who are experiencing acute suicidal ideation or behavior. It is used to rapidly reduce depressive symptoms in these critical situations as part of a comprehensive safety and treatment plan.
Safe, Monitored Administration
Because of its unique properties and for patient safety, spravato is only available at certified treatment centers like Myndful Wellness. Patients self-administer the nasal spray under the direct supervision of a healthcare provider, ensuring safety and comfort throughout the entire process.
A Non-Invasive Nasal Spray
Spravato is administered as a simple nasal spray, offering a convenient and non-invasive alternative to other forms of depression treatment. This unique delivery method allows for rapid absorption in a controlled, clinical setting.
Why Choose Our Compassionate Care?
Founded by Jessica Schmalz, PMHNP-BC, a board-certified psychiatric nurse practitioner, Myndful Wellness is a REMS-certified center for spravato. This certification reflects our commitment to the highest standards of patient safety and care protocols. A licensed psychiatric provider remains on-site throughout your visit, offering clinical oversight and therapeutic support in our private, comfortable treatment alcoves.

Our Spravato Process

Initial Consultation
Your journey begins with a comprehensive consultation to determine if spravato is right for you. We will review your medical history, previous treatments, and current symptoms to ensure you are a suitable candidate for this therapy.
Personalized Treatment Planning
If spravato is deemed appropriate, we will create a personalized treatment schedule. Our team will also help you navigate insurance coverage and patient assistance programs. Before insurance, the cost of treatment typically ranges from $550 to $950 per session.
Your Supervised Treatment Session
On treatment days, you will relax in a private, comfortable alcove. You will self-administer the spravato nasal spray under the direct supervision of one of our qualified providers who will guide you through the process.
Professional On-Site Monitoring
Following administration, you will rest comfortably in our office for a monitoring period of approximately two hours. A licensed psychiatric provider is always on-site to ensure your safety, manage potential side effects, and provide support.
Integrated Ongoing Care
Spravato is one part of your overall mental health plan. We integrate it with regular check-ins to monitor safety and effectiveness, adjusting your care plan as needed to support your long-term progress toward wellness.

Who Benefits from Spravato?
Myndful Wellness offers a path to relief with spravato for adults in Fruita, CO, facing treatment-resistant depression. Our clinic provides a supportive and professional setting for this innovative FDA-approved treatment. We are dedicated to helping our neighbors find new hope and achieve long-term mental wellness through personalized care plans.
Conditions We Treat

- Treatment-Resistant Depression (TRD)
- Major Depressive Disorder with Suicidal Ideation
- Adults Who Have Tried Other Antidepressants
- Patients Seeking Rapid Symptom Reduction
- Individuals in a Comprehensive Treatment Plan

Patient Experiences

“I am so grateful for the care I received at Myndful wellness. After struggling with my mental health for a long time, TMS and (Spravato)ketamine treatments helped me tremendously. I have noticed significant improvements in my mood, energy, and overall quality of life.”

“This place is awesome .I do my spravato treatments here. Jessica and Brittany are both very nice and professional especially Brittany and have always made me feel comfortable and not just like another patient.”

“I have been receiving ExxoMind and Spravano treatments for the past 3 months at Myndful Wellness. I was hesitant to begin treatment treatments that may seem out of the box but was well informed of what the benefits could actually mean for my depression. As I have progressed, I have felt very informed and taken care of.”
Cost of Spravato in Fruita, CO
Myndful Wellness offers a path to relief with spravato for adults in Fruita, CO, facing treatment-resistant depression. Our clinic provides a supportive and professional setting for this innovative FDA-approved treatment. We are dedicated to helping our neighbors find new hope and achieve long-term mental wellness through personalized care plans.
FAQ About Spravato in Fruita, CO
How often are Spravato treatments scheduled?
A typical schedule involves twice-weekly sessions for the first month, followed by weekly sessions, and then tapering to every other week as your condition improves. Your exact treatment frequency will be personalized by your provider.
Do I need to be a current patient to receive Spravato?
No, you do not need to be an established patient at our practice. We welcome referrals and new patients seeking a consultation to determine if spravato treatment is a good fit for their needs.
Is Spravato a standalone treatment for depression?
No, spravato is not a standalone therapy. It is required by the FDA to be used in combination with an oral antidepressant. It is one component of a comprehensive mental health plan that supports long-term recovery.
What does it mean that you are a REMS-certified center?
Being a REMS (Risk Evaluation and Mitigation Strategy) certified center means our clinic has met strict FDA requirements for prescribing and dispensing spravato. This program ensures we follow specific safety protocols to provide this treatment responsibly and effectively.