Spravato Treatment
in Grand Junction, CO
Myndful Wellness provides professional and compassionate care with spravato in Grand Junction, CO, for adults struggling with treatment-resistant depression. As a REMS-certified center, we offer this advanced, FDA-approved esketamine nasal spray as part of a comprehensive mental health plan. Our goal is to help you find relief and move toward long-term wellness when other treatments have not been effective. We are dedicated to providing a calm, supportive space for your healing journey.

What Is Spravato in Grand Junction, CO?
FDA-Approved Nasal Spray
Spravato is the first FDA-approved nasal spray formulation of esketamine, a compound related to ketamine. It is self-administered by the patient under the direct supervision of a healthcare provider in a certified medical office. This controlled administration ensures patient safety and adherence to the treatment protocol.
Unique Mechanism of Action
Unlike traditional antidepressants that primarily target serotonin or norepinephrine, spravato works on the NMDA receptor and the glutamate pathway. While its exact mechanism is still being studied, this different approach is believed to be why it can provide rapid relief for some patients with severe depression.
Certified REMS Center
Myndful Wellness is a certified spravato REMS (Risk Evaluation and Mitigation Strategy) treatment center. This certification means we adhere to strict FDA safety protocols, ensuring that the benefits of the treatment outweigh its risks. This includes patient monitoring and a controlled, safe environment for every session.
On-Site Professional Monitoring
During every treatment session, a licensed psychiatric provider from our team remains on-site to provide clinical oversight, therapeutic support, and continuous monitoring. Your safety and comfort are our highest priorities from the moment you arrive until you are cleared to go home with your pre-arranged transportation.
Integrated Treatment Approach
Spravato is not a standalone cure but a component of a comprehensive care plan. We integrate this therapy with your existing medication management and psychotherapy to achieve the best possible outcome. Our team collaborates with you and your other providers to ensure your treatment is cohesive.
Private and Comfortable Setting
We conduct all spravato treatments in private, comfortable alcoves designed to provide a calm and reassuring atmosphere. This allows you to relax in a safe space during the two-hour observation period following your treatment, with our team readily available to assist you.
Insurance and Cost Support
Navigating costs and coverage can be challenging, which is why our staff helps you with the insurance verification process. We also assist eligible patients in enrolling in the spravato withMe program, which may help reduce out-of-pocket expenses for your treatment.
Why Choose Our Compassionate Care?
Founded by Jessica Schmalz, MSN, APRN, PMHNP, PMH-C, our practice is built on a foundation of compassionate, individualized mental health care. We believe in a collaborative approach, viewing the connection between physical and emotional well-being as essential. Our team of qualified specialists at Myndful Wellness is dedicated to providing personalized care in a calm, supportive space for individuals across the Western Slope.

Our Spravato Process

Comprehensive Initial Assessment
Your journey begins with a thorough evaluation to determine if spravato is an appropriate option for your condition. We will review your mental health history, previous treatments, and current symptoms to create a personalized recommendation.
Insurance Verification and Planning
Once you are approved for treatment, our client services coordinator will guide you through the next steps. This includes verifying insurance coverage, discussing potential costs, and helping you enroll in any applicable savings programs.
Your Supervised Treatment Session
On treatment day, you will self-administer the spravato nasal spray under the direct supervision of our licensed provider. You will then rest comfortably in one of our private treatment alcoves for the duration of the session.
Post-Treatment Observation Period
For your safety, you will remain in our care for a mandatory two-hour observation period after your treatment. During this time, our team will monitor you for any side effects and ensure you are stable. You must have a pre-arranged ride home, as you will not be able to drive.
Ongoing Monitoring and Support
Spravato treatment involves an initial phase of sessions once or twice a week, followed by a maintenance phase with less frequent visits. We conduct regular check-ins to monitor your progress, assess safety, and adjust your overall mental health plan as needed to support your long-term wellness.

Who Benefits from Spravato?
Myndful Wellness provides professional and compassionate care with spravato in Grand Junction, CO, for adults struggling with treatment-resistant depression. As a REMS-certified center, we offer this advanced, FDA-approved esketamine nasal spray as part of a comprehensive mental health plan. Our goal is to help you find relief and move toward long-term wellness when other treatments have not been effective. We are dedicated to providing a calm, supportive space for your healing journey.
Conditions We Treat

- Treatment-Resistant Depression (TRD)
- Major Depressive Disorder with Suicidal Thoughts
- A History of Unsuccessful Treatments
- Need for a Rapid-Acting Intervention
- A Desire for a Non-Oral Treatment Option

Patient Experiences

“I am so grateful for the care I received at Myndful wellness. After struggling with my mental health for a long time, TMS and (Spravato)ketamine treatments helped me tremendously. I have noticed significant improvements in my mood, energy, and overall quality of life.”

“This place is awesome .I do my spravato treatments here. Jessica and Brittany are both very nice and professional especially Brittany and have always made me feel comfortable and not just like another patient.”

“I have been receiving ExxoMind and Spravano treatments for the past 3 months at Myndful Wellness. I was hesitant to begin treatment treatments that may seem out of the box but was well informed of what the benefits could actually mean for my depression. As I have progressed, I have felt very informed and taken care of.”
Cost of Spravato in Grand Junction, CO
Myndful Wellness provides professional and compassionate care with spravato in Grand Junction, CO, for adults struggling with treatment-resistant depression. As a REMS-certified center, we offer this advanced, FDA-approved esketamine nasal spray as part of a comprehensive mental health plan. Our goal is to help you find relief and move toward long-term wellness when other treatments have not been effective. We are dedicated to providing a calm, supportive space for your healing journey.
FAQ About Spravato in Grand Junction, CO
How is Spravato different from other antidepressants?
Unlike traditional antidepressants that affect serotonin, spravato works on the brain’s glutamate pathway via an NMDA receptor. This different biological approach is why it can provide rapid relief when other medications have not been successful.
What happens during a Spravato treatment session?
A treatment session involves self-administering the nasal spray under our supervision, followed by a two-hour monitoring period in a private, comfortable room. We ensure your safety throughout the visit. Patients cannot drive after treatment and must arrange for a ride home.
Is Spravato covered by my insurance?
Spravato is covered by many commercial insurance plans and Medicaid for its approved uses. Our administrative team will help verify your specific benefits and navigate prior authorization. We also assist eligible patients with enrolling in savings programs like spravato withMe to help lower out-of-pocket costs.
Do I need to be a regular patient to receive Spravato?
No, you do not need to have your other medications prescribed by Myndful Wellness to be considered for spravato. We collaborate with your existing mental health providers to ensure this treatment is safely integrated into your overall care plan. An initial assessment at our clinic is required to confirm eligibility.