Spravato Treatment
in Clifton, CO
Myndful Wellness provides access to innovative treatments like spravato in Clifton, CO, offering new hope for adults with persistent depression. This FDA-approved esketamine nasal spray is for individuals who have not found relief with other antidepressants. Our practice, located in Grand Junction, offers a supportive and clinically supervised environment for this advanced therapy.

What Is Spravato in Clifton, CO?
FDA-Approved Nasal Spray
Spravato (esketamine) is a prescription medication administered as a simple nasal spray. This delivery method is non-invasive and allows for precise dosing in a clinical setting.
For Treatment-Resistant Depression
This treatment is specifically indicated for adults with treatment-resistant depression (TRD). TRD is defined as major depressive disorder that has not responded adequately to at least two different oral antidepressant treatments.
Unique Mechanism of Action
Unlike traditional antidepressants that primarily target serotonin or norepinephrine, spravato works on the NMDA receptor, which is involved with the neurotransmitter glutamate. This distinct mechanism helps restore synaptic connections in brain cells affected by depression.
Administered Under Supervision
Due to its unique properties and to ensure patient safety, spravato is only administered in a certified healthcare setting. Patients self-administer the spray under the direct observation of a healthcare provider who monitors them for at least two hours.
Part of a Comprehensive Plan
Spravato is not a standalone treatment. It is prescribed alongside a daily oral antidepressant and is integrated into your comprehensive mental health plan, which may include therapy and other supportive care at Myndful Wellness.
REMS Certified Center
Myndful Wellness is a REMS (Risk Evaluation and Mitigation Strategy) certified treatment center. This certification means we meet the strict safety protocols required by the FDA to prescribe and administer spravato.
Insurance & Cost Support
Navigating treatment costs can be challenging, which is why our staff is here to help. We assist patients with verifying insurance coverage and accessing cost-saving programs like spravato withMe to make treatment more accessible.
Why Choose Our Compassionate Care?
Founded by Jessica Schmalz, PMHNP-BC, Myndful Wellness is built on a foundation of compassionate, individualized care. We understand the deep connection between physical and mental health, ensuring your spravato treatment is part of a holistic wellness journey. Our team provides a calm, supportive space where your long-term well-being is the primary focus.

Our Spravato Process

Initial Assessment
Your journey begins with a thorough psychiatric evaluation to determine if spravato is a suitable option for your condition. We will review your treatment history and discuss the potential benefits and process with you.
Treatment Planning & Scheduling
Once you are approved for treatment, our team will work with your insurance provider and help you with any necessary paperwork. We will then schedule your first series of appointments, which typically occur once or twice per week.
Your Supervised Treatment Session
On treatment day, you will relax in a private, comfortable room. You will self-administer the spravato nasal spray under the guidance of our staff, who will be present to ensure you are comfortable and safe.
Post-Treatment Observation
Following administration, you will rest comfortably in our office for a mandatory two-hour observation period. A licensed psychiatric provider remains on-site to monitor your response and provide support. You must arrange for transportation home after your session.
Ongoing Follow-Up Care
Your progress is closely monitored with regular check-ins to assess safety and effectiveness. We integrate these sessions into your broader mental health plan, adjusting as needed to support your long-term wellness goals.

Who Benefits from Spravato?
Myndful Wellness provides access to innovative treatments like spravato in Clifton, CO, offering new hope for adults with persistent depression. This FDA-approved esketamine nasal spray is for individuals who have not found relief with other antidepressants. Our practice, located in Grand Junction, offers a supportive and clinically supervised environment for this advanced therapy.
Conditions We Treat

- Diagnosed with Treatment-Resistant Depression (TRD)
- Experiencing MDD with Suicidal Thoughts or Behavior
- Have Not Responded to Two or More Antidepressants
- Willing to Continue an Oral Antidepressant
- Able to Attend Monitored In-Office Appointments

Patient Experiences

“I am so grateful for the care I received at Myndful wellness. After struggling with my mental health for a long time, TMS and (Spravato)ketamine treatments helped me tremendously. I have noticed significant improvements in my mood, energy, and overall quality of life.”

“This place is awesome .I do my spravato treatments here. Jessica and Brittany are both very nice and professional especially Brittany and have always made me feel comfortable and not just like another patient.”

“I have been receiving ExxoMind and Spravano treatments for the past 3 months at Myndful Wellness. I was hesitant to begin treatment treatments that may seem out of the box but was well informed of what the benefits could actually mean for my depression. As I have progressed, I have felt very informed and taken care of.”
Cost of Spravato in Clifton, CO
Myndful Wellness provides access to innovative treatments like spravato in Clifton, CO, offering new hope for adults with persistent depression. This FDA-approved esketamine nasal spray is for individuals who have not found relief with other antidepressants. Our practice, located in Grand Junction, offers a supportive and clinically supervised environment for this advanced therapy.
FAQ About Spravato in Clifton, CO
How is Spravato different from other antidepressants?
While most antidepressants focus on neurotransmitters like serotonin, spravato works on the glutamate system. This unique mechanism can help restore brain cell connections affected by depression, making it effective when other medications have not provided relief.
What happens during a Spravato treatment session?
Each session occurs in a private room at our clinic. You will self-administer the nasal spray under our supervision and then relax for a two-hour observation period. Our medical team monitors you throughout to ensure your safety and comfort.
Do I need to be a regular patient for Spravato treatment?
No, you do not need to be an established patient at our practice. We welcome referrals and can collaborate with your existing mental health provider to integrate spravato into your care plan.
How often will I need to come in for treatment?
The initial treatment phase typically involves sessions once or twice a week for the first month. Afterward, your provider will work with you to create a less frequent maintenance schedule based on your individual response and progress.